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Gonorrhea is a sexually transmitted disease (STD) caused by the bacterium Neisseria gonorrhea. It tends to infect urethra, vagina, anus, and other sexual organs; even eye or throat area may be affected sometimes. Gonorrhea passes from one person to another due to unprotected sexual practices or persons who have multiple sexual partners.

The World Health Organization (WHO) estimated that the global incidence of gonorrhea increased from 87.7 million in 2005 to 106.1 million in 2008. An article published by Newman et al (2015) estimated the global prevalence of gonorrhea at 0.8% among women aged 15 years to 49 years and 0.6% among men in the same age group in 2012. Rise in new cases of gonorrhea, public awareness about the disease, high rate of diagnosis, high risk of complications, novel therapeutic options, and government regulations about antibiotic uses are the major drivers of the global gonorrhea therapeutics market. However, antibiotic-resistant gonorrhea is a growing concern among physicians.

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A combination vaccine is designed to provide protection against two or more diseases or against single disease caused by completely different or similar organism. A combination vaccine also boosts the immune system to fight against infection. These vaccines contain two or more antigens that are either combined in ready form or mixed before administration. Safety, efficacy, and immunogenicity of a combined immunizing agent are high. 

Pheochromocytoma is an efficient catecholamine-secreting tumor of the adrenal gland medulla. Catecholamines include norepinephrine, epinephrine, and their derivatives. Symptoms of pheochromocytoma include flank skin, elevated heart rate, elevated blood pressure, anxiety, sweating, headache, and weight loss. Within normal limits, norepinephrine and epinephrine hormones are responsible for regulating the blood pressure and heart rate. Excess production of catecholamine due to pheochromocytoma is a reason for high blood pressure with life-threatening and potentially serious difficulties such as stroke and heart attack. Pheochromocytoma occurs most frequently in adults aged between 30 and 60 years. Pheochromocytomas are not life-threatening mostly, but have 10% chances of being cancerous. High blood pressure is the most significant symptom; however, excessive sweating, light-headedness, a fast and pounding pulse when standing, severe headache, rapid breathing, and other symptoms may also occur.

Snakebite envenoming is a catastrophic global health issue that kills and incapacitates millions of people annually. It has been declared a global public health emergency. Empirical data suggests that an accurate information on the burden of snakebite is unavailable and this has resulted in epidemiological knowledge gap in this field. Research findings from more than 100 countries spread across 21 geographical regions have brought to light that at least 421,000 envenomings and 20,000 snakebite deaths occur each year globally. However, the expected toll could be as high as 1,841,000 envenomings and 94,000 deaths due to snakebite globally. The highest burden of snakebites is witnessed in regions such as South Asia, South East Asia, sub-Saharan Africa, and Latin America.

Anti-parasitic drugs are medications that are used for the treatment of parasitic diseases caused by parasites such as fungi and protozoa. These drugs destroy or inhibit the growth of parasitic agents by targeting them. In a particular class, these medications are effective to a limited number of parasites. Parasitic infections can be severe, moderate, or mild. Ascariasis is one of the prevalent parasitic diseases. Other common infections are hookworm disease, trichomoniasis, and toxoplasmosis. The parasitic infections can result in nutritional deficiencies, fetal or neonatal harm, cutaneous nodules, and skin eruptions. Moreover, the infections may cause major damages to the central nervous system, lungs, eyes, heart, and liver. Anti-parasitic medications can be administered orally or intravenously, and these are one of the antimicrobial agents that include antibiotics that target bacteria. The World Health Organization (WHO) has suggested for public beneficial for the treatment of parasitic worm infections. Almost all of the common parasitic worm infections in the human body can be cured with one of five anthelmintics currently in use: mebendazole, albendazole, diethylcarbamazine, praziquantel, and ivermectin. The purpose of the anthelmintic treatment is to moderate the intensity of the infection beneath the level of clinical significance.

Personalized therapy is related to the genetic makeup of a person. It helps doctors to understand how a tumor grows in a particular patient to identify effective screening, control, and treatment methods. : Doctors are engaged in developing novel treatments with fewer side effects as compared to the traditional treatments. Doctors perform various genetic tests on cancer cells and on normal cells, to develop new customized treatment according to the patient’s needs.

Before personalized therapy, most patients with a specific stage and type of cancer received similar treatment. However, it is evident that certain treatments work specifically on some patients and give better results, as compare to other patients. Development in the field of genetics has led scientists to identify genetic differences in certain patients and their cancer, this described several other responses to treatment. A cancer patient can obtain a standard treatment strategy, such as tumor removal. The doctors can prescribed a personalized cancer treatment. Personalized therapy is an important part of cancer treatment or a part of the clinical trial. A clinical trial is an investigation study including people.

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Taxoplasmosis encephalitis is an infection caused by Taxoplasma gondii, an intracellular protozoan parasite. The infection can occur pre-natally or post-natally. It may be caused by exposure or consumption of undercooked meat, drinking of unpasteurized goat milk, contact with soil, cleaning of cat litter boxes, and ingestion of unwashed raw fruits or vegetables. The infection can also occur during organ transplantation or due to laboratory accidents. Prevalence of the infection varies from country to country. The prevalence is high in Latin America and countries of tropical Africa. North America, Southeast Asia, Northern Europe, and Africa witness low sero-prevalence, while Central and Southern Europe witness moderate prevalence of the disease.

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Future Market Insights (FMI) delivers key insights on the global spinal fusion market in its upcoming report titled “Spinal Fusion Market: Global Industry Analysis 2012–2016 and Opportunity Assessment 2017 – 2027.” In terms of revenue, the global spinal fusion market is projected to register a CAGR of 5.4% over the forecast period, owing to various factors, regarding which FMI offers detailed insights and forecasts in this report. A key trend witnessed in the global spinal fusion market is the rise in the development of minimising load due to increasing adverse reactions. Furthermore, the growing importance of developing advanced products among big players to enhance their product portfolio is another key trend in the global spinal fusion market.

Market Segmentation and Forecast

In its newly compiled report, Future Market Insights (FMI) states that the global niacin and niacinamide market will showcase a steady rise over the forecast period, 2017 to 2026. Sales of niacin and niacinamide across the globe are estimated to reach revenues worth approximately US$ 1,500 Mn by 2026-end.

Key Takeaways from FMI’s Report on Niacin and Niacinamide Market for the Forecast Period 2017-2026

Liquid and granular forms of niacin and niacinamide are expected to witness the fastest sales expansion through 2026. However, market revenue share of powder form of niacin and niacinamide will remain comparatively higher than the combined share of powder and liquid forms throughout the forecast period.

Sales of niacin and niacinamide for end-use in cosmeceuticals and human nutrition will ride on the highest CAGRs through 2026. In contrast, niacin and niacinamide sales for end-use in animal nutrition will register the lowest CAGR, albeit this end-use segment is projected to account for the highest revenue share over the forecast period. Pharmaceuticals will remain a steadily expanding end-use of niacin and niacinamide.